产品名称

TIGIT (AFN0530) Nb-FC recombinant antibody

产品货号

AFNM0645

基因名称

TIGIT VSIG9 VSTM3

蛋白名称

T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3)

其他名称

T-cell immunoreceptor with Ig and ITIM domains;VSIG9;VSTM3;WUCAM;TIGIT nanobody;

Gene ID

Human:201633    

SwissPro

Human:Q495A1    

宿主种属

Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell

应用范围

ELISA

稀释比例

ELISA 1:5000-100000

反应种属

Human

克隆性

Monoclonal

免疫原

Purified recombinant Human TIGIT

特异性

This recombinant monoclonal antibody can detects endogenous levels of TIGIT protein.

保存液

Phosphate-buffered solution

纯化方式

Recombinant Expression and Affinity purified

产品浓度

Please check the information on the tube

保存条件

-15°C to -25°C/1 year(Avoid freeze / thaw cycles)

背景资料

T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as VSTM3 or WUCAM, is a 26 kD, type I transmembrane protein and is a member of the PVR (poliovirus receptor) family of immunoglobulin-like domain containing proteins. TIGIT is expressed on activated T cells, follicular T helper, memory, and regulatory T cells as well as on NK cells. TIGIT is a negative regulator of NK and T cell activation. Expression of TIGIT is associated with decreased functionality of CD8 T cells in chronic v